Discordance between Bovine Leukemia Virus Tax Immortalization In Vitro and Oncogenicity In Vivo

Bovine leukemia virus (BLV) Tax protein, a transcriptional activator of viral expression, is essential for viral replication in vivo. Tax is believed to be involved in leukemogenesis because of its second function, immortalization of primary cells in vitro. These activities of Tax can be dissociated...

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Podrobná bibliografie

Vydáno v:	J Virol
Hlavní autoři:	Twizere, Jean-Claude, Kerkhofs, Pierre, Burny, Arsène, Portetelle, Daniel, Kettmann, Richard, Willems, Luc
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	American Society for Microbiology (ASM) 2000
Témata:	Transformation and Oncogenesis
On-line přístup:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC102026/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11024116/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.74.21.9895-9902.2000
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