Discordance between Bovine Leukemia Virus Tax Immortalization In Vitro and Oncogenicity In Vivo

Bovine leukemia virus (BLV) Tax protein, a transcriptional activator of viral expression, is essential for viral replication in vivo. Tax is believed to be involved in leukemogenesis because of its second function, immortalization of primary cells in vitro. These activities of Tax can be dissociated...

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Библиографические подробности
Главные авторы: Twizere, Jean-Claude, Kerkhofs, Pierre, Burny, Arsène, Portetelle, Daniel, Kettmann, Richard, Willems, Luc
Формат: Artigo
Язык:Inglês
Опубликовано: American Society for Microbiology 2000
Предметы:
Transformation and Oncogenesis
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC102026/
https://ncbi.nlm.nih.gov/pubmed/11024116
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