Discordance between Bovine Leukemia Virus Tax Immortalization In Vitro and Oncogenicity In Vivo

Bovine leukemia virus (BLV) Tax protein, a transcriptional activator of viral expression, is essential for viral replication in vivo. Tax is believed to be involved in leukemogenesis because of its second function, immortalization of primary cells in vitro. These activities of Tax can be dissociated...

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Εκδόθηκε σε:	J Virol
Κύριοι συγγραφείς:	Twizere, Jean-Claude, Kerkhofs, Pierre, Burny, Arsène, Portetelle, Daniel, Kettmann, Richard, Willems, Luc
Μορφή:	Artigo
Γλώσσα:	Inglês
Έκδοση:	American Society for Microbiology (ASM) 2000
Θέματα:	Transformation and Oncogenesis
Διαθέσιμο Online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC102026/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11024116/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.74.21.9895-9902.2000
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