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Discordance between Bovine Leukemia Virus Tax Immortalization In Vitro and Oncogenicity In Vivo

Bovine leukemia virus (BLV) Tax protein, a transcriptional activator of viral expression, is essential for viral replication in vivo. Tax is believed to be involved in leukemogenesis because of its second function, immortalization of primary cells in vitro. These activities of Tax can be dissociated...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Twizere, Jean-Claude, Kerkhofs, Pierre, Burny, Arsène, Portetelle, Daniel, Kettmann, Richard, Willems, Luc
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Society for Microbiology 2000
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC102026/
https://ncbi.nlm.nih.gov/pubmed/11024116
Tagiau: Ychwanegu Tag
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