Discordance between Bovine Leukemia Virus Tax Immortalization In Vitro and Oncogenicity In Vivo

Bovine leukemia virus (BLV) Tax protein, a transcriptional activator of viral expression, is essential for viral replication in vivo. Tax is believed to be involved in leukemogenesis because of its second function, immortalization of primary cells in vitro. These activities of Tax can be dissociated...

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Detalles Bibliográficos

Publicado en:	J Virol
Autores principales:	Twizere, Jean-Claude, Kerkhofs, Pierre, Burny, Arsène, Portetelle, Daniel, Kettmann, Richard, Willems, Luc
Formato:	Artigo
Lenguaje:	Inglês
Publicado:	American Society for Microbiology (ASM) 2000
Materias:	Transformation and Oncogenesis
Acceso en línea:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC102026/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11024116/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.74.21.9895-9902.2000
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