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Hepatitis C Virus Core from Two Different Genotypes Has an Oncogenic Potential but Is Not Sufficient for Transforming Primary Rat Embryo Fibroblasts in Cooperation with the H-ras Oncogene

Persistent infection with hepatitis C virus (HCV) is associated with the development of liver cirrhosis and hepatocellular carcinoma. To examine the oncogenic potential of the HCV core gene product, primary rat embryo fibroblasts (REFs) were transfected with the core gene in the presence or absence...

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Detalhes bibliográficos
Main Authors: Chang, Jun, Yang, Se-Hwan, Cho, Young-Gyu, Hwang, Soon Bong, Hahn, Young Shin, Sung, Young Chul
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 1998
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC109754/
https://ncbi.nlm.nih.gov/pubmed/9525629
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