Intracellular Penetration and Activity of Gemifloxacin in Human Polymorphonuclear Leukocytes

The intracellular penetration and activity of gemifloxacin in human polymorphonuclear leukocytes (PMN) were evaluated. Gemifloxacin reached intracellular concentrations eight times higher than extracellular concentrations. The uptake was rapid, reversible, and nonsaturable and was affected by enviro...

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書誌詳細

出版年:	Antimicrob Agents Chemother
主要な著者:	García, Isabel, Pascual, Alvaro, Ballesta, Sofía, Joyanes, Providencia, Perea, Evelio J.
フォーマット:	Artigo
言語:	Inglês
出版事項:	American Society for Microbiology (ASM) 2000
主題:	Susceptibility
オンライン･アクセス:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC101631/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11036051/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.44.11.3193-3195.2000
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