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Intracellular Penetration and Activity of Gemifloxacin in Human Polymorphonuclear Leukocytes

The intracellular penetration and activity of gemifloxacin in human polymorphonuclear leukocytes (PMN) were evaluated. Gemifloxacin reached intracellular concentrations eight times higher than extracellular concentrations. The uptake was rapid, reversible, and nonsaturable and was affected by enviro...

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Hlavní autoři: García, Isabel, Pascual, Alvaro, Ballesta, Sofía, Joyanes, Providencia, Perea, Evelio J.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2000
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC101631/
https://ncbi.nlm.nih.gov/pubmed/11036051
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