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Intracellular Penetration and Activity of Gemifloxacin in Human Polymorphonuclear Leukocytes

The intracellular penetration and activity of gemifloxacin in human polymorphonuclear leukocytes (PMN) were evaluated. Gemifloxacin reached intracellular concentrations eight times higher than extracellular concentrations. The uptake was rapid, reversible, and nonsaturable and was affected by enviro...

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Detalhes bibliográficos
Main Authors: García, Isabel, Pascual, Alvaro, Ballesta, Sofía, Joyanes, Providencia, Perea, Evelio J.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2000
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC101631/
https://ncbi.nlm.nih.gov/pubmed/11036051
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