Intracellular Penetration and Activity of Gemifloxacin in Human Polymorphonuclear Leukocytes

The intracellular penetration and activity of gemifloxacin in human polymorphonuclear leukocytes (PMN) were evaluated. Gemifloxacin reached intracellular concentrations eight times higher than extracellular concentrations. The uptake was rapid, reversible, and nonsaturable and was affected by enviro...

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Dades bibliogràfiques

Publicat a:	Antimicrob Agents Chemother
Autors principals:	García, Isabel, Pascual, Alvaro, Ballesta, Sofía, Joyanes, Providencia, Perea, Evelio J.
Format:	Artigo
Idioma:	Inglês
Publicat:	American Society for Microbiology (ASM) 2000
Matèries:	Susceptibility
Accés en línia:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC101631/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11036051/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.44.11.3193-3195.2000
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