Uptake and intracellular activity of sparfloxacin in human polymorphonuclear leukocytes and tissue culture cells.
The penetration of sparfloxacin into human neutrophils (PMN) and different tissue culture cells (HEp-2 and McCoy) was evaluated. The cellular to extracellular concentration ratios (C/E) of sparfloxacin were always higher than 4 at extracellular concentrations ranging from 0.5 to 25 mg/liter. The upt...
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| Publicado no: | Antimicrob Agents Chemother |
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| Principais autores: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Microbiology (ASM)
1992
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC188834/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1324636/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.36.5.1053 |
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