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Uptake and intracellular activity of sparfloxacin in human polymorphonuclear leukocytes and tissue culture cells.

The penetration of sparfloxacin into human neutrophils (PMN) and different tissue culture cells (HEp-2 and McCoy) was evaluated. The cellular to extracellular concentration ratios (C/E) of sparfloxacin were always higher than 4 at extracellular concentrations ranging from 0.5 to 25 mg/liter. The upt...

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Detalhes bibliográficos
Main Authors: García, I, Pascual, A, Guzman, M C, Perea, E J
Formato: Artigo
Idioma:Inglês
Publicado em: 1992
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC188834/
https://ncbi.nlm.nih.gov/pubmed/1324636
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