Uptake and intracellular activity of sparfloxacin in human polymorphonuclear leukocytes and tissue culture cells.

The penetration of sparfloxacin into human neutrophils (PMN) and different tissue culture cells (HEp-2 and McCoy) was evaluated. The cellular to extracellular concentration ratios (C/E) of sparfloxacin were always higher than 4 at extracellular concentrations ranging from 0.5 to 25 mg/liter. The upt...

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izdano v:	Antimicrob Agents Chemother
Principais autores:	García, I, Pascual, A, Guzman, M C, Perea, E J
Format:	Artigo
Jezik:	Inglês
Izdano:	American Society for Microbiology (ASM) 1992
Teme:	Research Article
Online dostop:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC188834/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1324636/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.36.5.1053
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