Intracellular Penetration and Activity of Gemifloxacin in Human Polymorphonuclear Leukocytes

The intracellular penetration and activity of gemifloxacin in human polymorphonuclear leukocytes (PMN) were evaluated. Gemifloxacin reached intracellular concentrations eight times higher than extracellular concentrations. The uptake was rapid, reversible, and nonsaturable and was affected by enviro...

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Detalhes bibliográficos

Publicado no:	Antimicrob Agents Chemother
Principais autores:	García, Isabel, Pascual, Alvaro, Ballesta, Sofía, Joyanes, Providencia, Perea, Evelio J.
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 2000
Assuntos:	Susceptibility
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC101631/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11036051/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.44.11.3193-3195.2000
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