Methylation-dependent silencing at the H19 imprinting control region by MeCP2
Methylation of CpG dinucleotides is correlated with transcriptional repression of genes, including imprinted genes. In the case of the imprinted H19 gene, a 2 kb imprinting control region (ICR) is subject to differential methylation, as it is methylated only on the silenced paternal allele. This reg...
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| Publicado no: | Nucleic Acids Res |
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| Principais autores: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2002
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC101245/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11861904/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/30.5.1139 |
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