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Methylation-dependent silencing at the H19 imprinting control region by MeCP2

Methylation of CpG dinucleotides is correlated with transcriptional repression of genes, including imprinted genes. In the case of the imprinted H19 gene, a 2 kb imprinting control region (ICR) is subject to differential methylation, as it is methylated only on the silenced paternal allele. This reg...

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Bibliografische gegevens
Gepubliceerd in:Nucleic Acids Res
Hoofdauteurs: Drewell, Robert A., Goddard, Carolyn J., Thomas, Jean O., Surani, M. Azim
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Oxford University Press 2002
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Online toegang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC101245/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11861904/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/30.5.1139
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