Methylation-dependent silencing at the H19 imprinting control region by MeCP2

Methylation of CpG dinucleotides is correlated with transcriptional repression of genes, including imprinted genes. In the case of the imprinted H19 gene, a 2 kb imprinting control region (ICR) is subject to differential methylation, as it is methylated only on the silenced paternal allele. This reg...

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Vydáno v:	Nucleic Acids Res
Hlavní autoři:	Drewell, Robert A., Goddard, Carolyn J., Thomas, Jean O., Surani, M. Azim
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	Oxford University Press 2002
Témata:	Article
On-line přístup:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC101245/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11861904/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/30.5.1139
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