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Methylation-dependent silencing at the H19 imprinting control region by MeCP2

Methylation of CpG dinucleotides is correlated with transcriptional repression of genes, including imprinted genes. In the case of the imprinted H19 gene, a 2 kb imprinting control region (ICR) is subject to differential methylation, as it is methylated only on the silenced paternal allele. This reg...

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Bibliografiset tiedot
Julkaisussa:Nucleic Acids Res
Päätekijät: Drewell, Robert A., Goddard, Carolyn J., Thomas, Jean O., Surani, M. Azim
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Oxford University Press 2002
Aiheet:
Linkit:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC101245/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11861904/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/30.5.1139
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