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The MT domain of the proto-oncoprotein MLL binds to CpG-containing DNA and discriminates against methylation
Alterations of the proto-oncogene MLL (mixed lineage leukemia) are characteristic for a high proportion of acute leukemias, especially those occurring in infants. The activation of MLL is achieved either by an internal tandem duplication of 5′ MLL exons or by chromosomal translocations that create c...
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| 主要な著者: | , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Oxford University Press
2002
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC100340/ https://ncbi.nlm.nih.gov/pubmed/11842107 |
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