The MT domain of the proto-oncoprotein MLL binds to CpG-containing DNA and discriminates against methylation

Alterations of the proto-oncogene MLL (mixed lineage leukemia) are characteristic for a high proportion of acute leukemias, especially those occurring in infants. The activation of MLL is achieved either by an internal tandem duplication of 5′ MLL exons or by chromosomal translocations that create c...

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Detalhes bibliográficos

Publicado no:	Nucleic Acids Res
Principais autores:	Birke, Marco, Schreiner, Silke, García-Cuéllar, María-Paz, Mahr, Kerstin, Titgemeyer, Fritz, Slany, Robert K.
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Oxford University Press 2002
Assuntos:	Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC100340/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11842107/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/30.4.958
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