Mbd1 Is Recruited to both Methylated and Nonmethylated CpGs via Distinct DNA Binding Domains

MBD1 is a vertebrate methyl-CpG binding domain protein (MBD) that can bring about repression of methylated promoter DNA sequences. Like other MBD proteins, MBD1 localizes to nuclear foci that in mice are rich in methyl-CpG. In methyl-CpG-deficient mouse cells, however, Mbd1 remains localized to hete...

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Detalhes bibliográficos

Publicado no:	Mol Cell Biol
Principais autores:	Jørgensen, Helle F., Ben-Porath, Ittai, Bird, Adrian P.
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Taylor & Francis 2004
Assuntos:	DNA Dynamics and Chromosome Structure
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC381685/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15060159/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/MCB.24.8.3387-3395.2004
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