Transformation of myeloid progenitors by MLL oncoproteins is dependent on Hoxa7 and Hoxa9
Transcriptional deregulation through the production of dominant-acting chimeric transcription factors derived from chromosomal translocations is a common theme in the pathogenesis of acute leukemias; however, the essential target genes for acute leukemogenesis are unknown. We demonstrate here that p...
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| Udgivet i: | Genes Dev |
|---|---|
| Principais autores: | , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Cold Spring Harbor Laboratory Press
2003
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC196466/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12952893/ https://ncbi.nlm.nih.govhttps://doi.org/10.1101/gad.1111603 |
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