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Transformation of myeloid progenitors by MLL oncoproteins is dependent on Hoxa7 and Hoxa9

Transcriptional deregulation through the production of dominant-acting chimeric transcription factors derived from chromosomal translocations is a common theme in the pathogenesis of acute leukemias; however, the essential target genes for acute leukemogenesis are unknown. We demonstrate here that p...

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Detalhes bibliográficos
Main Authors: Ayton, Paul M., Cleary, Michael L.
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2003
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC196466/
https://ncbi.nlm.nih.gov/pubmed/12952893
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.1111603
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