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Protein Interactions of the MLL PHD Fingers Modulate MLL Target Gene Regulation in Human Cells
The PHD fingers of the human MLL and Drosophila trx proteins have strong amino acid sequence conservation but their function is unknown. We have determined that these fingers mediate homodimerization and binding of MLL to Cyp33, a nuclear cyclophilin. These two proteins interact in vitro and in vivo...
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| 主要な著者: | , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
American Society for Microbiology
2001
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC100280/ https://ncbi.nlm.nih.gov/pubmed/11313484 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.21.10.3589-3597.2001 |
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