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Protein Interactions of the MLL PHD Fingers Modulate MLL Target Gene Regulation in Human Cells

The PHD fingers of the human MLL and Drosophila trx proteins have strong amino acid sequence conservation but their function is unknown. We have determined that these fingers mediate homodimerization and binding of MLL to Cyp33, a nuclear cyclophilin. These two proteins interact in vitro and in vivo...

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書誌詳細
主要な著者: Fair, Keri, Anderson, Melanie, Bulanova, Elena, Mi, Huaifeng, Tropschug, Maximilian, Diaz, Manuel O.
フォーマット: Artigo
言語:Inglês
出版事項: American Society for Microbiology 2001
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC100280/
https://ncbi.nlm.nih.gov/pubmed/11313484
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.21.10.3589-3597.2001
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