Role of DNA Polymerase η in the Bypass of a (6-4) TT Photoproduct

UV light-induced DNA lesions block the normal replication machinery. Eukaryotic cells possess DNA polymerase η (Polη), which has the ability to replicate past a cis-syn thymine-thymine (TT) dimer efficiently and accurately, and mutations in human Polη result in the cancer-prone syndrome, the variant...

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Dades bibliogràfiques

Publicat a:	Mol Cell Biol
Autors principals:	Johnson, Robert E., Haracska, Lajos, Prakash, Satya, Prakash, Louise
Format:	Artigo
Idioma:	Inglês
Publicat:	Taylor & Francis 2001
Matèries:	DNA Dynamics and Chromosome Structure
Accés en línia:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC100277/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11313481/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/MCB.21.10.3558-3563.2001
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