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Impact of Natural Compounds on DNA Methylation Levels of the Tumor Suppressor Gene RASSF1A in Cancer

Epigenetic inactivation of tumor suppressor genes (TSG) is a fundamental event in the pathogenesis of human cancer. This silencing is accomplished by aberrant chromatin modifications including DNA hypermethylation of the gene promoter. One of the most frequently hypermethylated TSG in human cancer i...

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Main Authors: Reinhard H. Dammann, Antje M. Richter, Adriana P. Jiménez, Michelle Woods, Miriam Küster, Chamindri Witharana
格式: Artigo
語言:Inglês
出版: MDPI AG 2017-10-01
叢編:International Journal of Molecular Sciences
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在線閱讀:https://www.mdpi.com/1422-0067/18/10/2160
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