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RASSF10 Is a TGFβ-Target That Regulates ASPP2 and E-Cadherin Expression and Acts as Tumor Suppressor That Is Epigenetically Downregulated in Advanced Cancer

The Ras Association Domain Family (RASSF) encodes members of tumor suppressor genes which are frequently inactivated in human cancers. Here, the function and the regulation of RASSF10, that contains a RA (Ras-association) and two coiled domains, was investigated. We utilized mass spectrometry and im...

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Detalhes bibliográficos
Publicado no:Cancers (Basel)
Main Authors: Richter, Antje M., Küster, Miriam M., Woods, Michelle L., Walesch, Sara K., Gökyildirim, Mira Y., Krueger, Marcus, Dammann, Reinhard H.
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6966473/
https://ncbi.nlm.nih.gov/pubmed/31817988
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers11121976
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