Impact of Natural Compounds on DNA Methylation Levels of the Tumor Suppressor Gene RASSF1A in Cancer

Epigenetic inactivation of tumor suppressor genes (TSG) is a fundamental event in the pathogenesis of human cancer. This silencing is accomplished by aberrant chromatin modifications including DNA hypermethylation of the gene promoter. One of the most frequently hypermethylated TSG in human cancer i...

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Vydáno v:Int J Mol Sci
Hlavní autoři: Dammann, Reinhard H., Richter, Antje M., Jiménez, Adriana P., Woods, Michelle, Küster, Miriam, Witharana, Chamindri
Médium: Artigo
Jazyk:Inglês
Vydáno: MDPI 2017
Témata:
Review
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5666841/
https://ncbi.nlm.nih.gov/pubmed/29039788
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms18102160
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