Impact of Natural Compounds on DNA Methylation Levels of the Tumor Suppressor Gene RASSF1A in Cancer

Epigenetic inactivation of tumor suppressor genes (TSG) is a fundamental event in the pathogenesis of human cancer. This silencing is accomplished by aberrant chromatin modifications including DNA hypermethylation of the gene promoter. One of the most frequently hypermethylated TSG in human cancer i...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
मुख्य लेखकों: Reinhard H. Dammann, Antje M. Richter, Adriana P. Jiménez, Michelle Woods, Miriam Küster, Chamindri Witharana
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: MDPI AG 2017-10-01
श्रृंखला:International Journal of Molecular Sciences
विषय:
DNA methylation
tumor suppressor gene
RASSF1
demethylation
natural compounds
ऑनलाइन पहुंच:https://www.mdpi.com/1422-0067/18/10/2160
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