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Impact of Natural Compounds on DNA Methylation Levels of the Tumor Suppressor Gene RASSF1A in Cancer

Epigenetic inactivation of tumor suppressor genes (TSG) is a fundamental event in the pathogenesis of human cancer. This silencing is accomplished by aberrant chromatin modifications including DNA hypermethylation of the gene promoter. One of the most frequently hypermethylated TSG in human cancer i...

詳細記述

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書誌詳細
主要な著者: Reinhard H. Dammann, Antje M. Richter, Adriana P. Jiménez, Michelle Woods, Miriam Küster, Chamindri Witharana
フォーマット: Artigo
言語:Inglês
出版事項: MDPI AG 2017-10-01
シリーズ:International Journal of Molecular Sciences
主題:
オンライン・アクセス:https://www.mdpi.com/1422-0067/18/10/2160
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