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Impact of Natural Compounds on DNA Methylation Levels of the Tumor Suppressor Gene RASSF1A in Cancer
Epigenetic inactivation of tumor suppressor genes (TSG) is a fundamental event in the pathogenesis of human cancer. This silencing is accomplished by aberrant chromatin modifications including DNA hypermethylation of the gene promoter. One of the most frequently hypermethylated TSG in human cancer i...
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主要な著者: | , , , , , |
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フォーマット: | Artigo |
言語: | Inglês |
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MDPI AG
2017-10-01
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シリーズ: | International Journal of Molecular Sciences |
主題: | |
オンライン・アクセス: | https://www.mdpi.com/1422-0067/18/10/2160 |
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