SpeB of Streptococcus pyogenes differentially modulates antibacterial and receptor activating properties of human chemokines.

BACKGROUND: CXC chemokines are induced by inflammatory stimuli in epithelial cells and some, like MIG/CXCL9, IP-10/CXCL10 and I-TAC/CXCL11, are antibacterial for Streptococcus pyogenes. METHODOLOGY/PRINCIPAL FINDINGS: SpeB from S. pyogenes degrades a wide range of chemokines (i.e. IP10/CXCL10, I-TAC...

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Bibliografiske detaljer
Main Authors: Arne Egesten, Anders I Olin, Helena M Linge, Manisha Yadav, Matthias Mörgelin, Anna Karlsson, Mattias Collin
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science (PLoS) 2009-01-01
Serier:PLoS ONE
Online adgang:http://europepmc.org/articles/PMC2652026?pdf=render
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