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Effect of SpeB and EndoS from Streptococcus pyogenes on Human Immunoglobulins
Streptococcus pyogenes secretes a specific immunoglobulin G (IgG)-protease, SpeB, as well as the IgG glycan-hydrolyzing enzyme EndoS. Here we show that SpeB also degrades IgA, IgM, IgD, and IgE. We also show that EndoS only hydrolyzes the glycan moiety on native but not denatured IgG. Thus, SpeB has...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Microbiology
2001
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC100124/ https://ncbi.nlm.nih.gov/pubmed/11598100 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.69.11.7187-7189.2001 |
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