Effect of SpeB and EndoS from Streptococcus pyogenes on Human Immunoglobulins

Streptococcus pyogenes secretes a specific immunoglobulin G (IgG)-protease, SpeB, as well as the IgG glycan-hydrolyzing enzyme EndoS. Here we show that SpeB also degrades IgA, IgM, IgD, and IgE. We also show that EndoS only hydrolyzes the glycan moiety on native but not denatured IgG. Thus, SpeB has...

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Detaylı Bibliyografya
Asıl Yazarlar: Collin, Mattias, Olsén, Arne
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society for Microbiology 2001
Konular:
Molecular Pathogenesis
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC100124/
https://ncbi.nlm.nih.gov/pubmed/11598100
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.69.11.7187-7189.2001
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