EndoS from <it>Streptococcus pyogenes </it>is hydrolyzed by the cysteine proteinase SpeB and requires glutamic acid 235 and tryptophans for IgG glycan-hydrolyzing activity
<p>Abstract</p> <p>Background</p> <p>The endoglycosidase EndoS and the cysteine proteinase SpeB from the human pathogen <it>Streptococcus pyogenes </it>are functionally related in that they both hydrolyze IgG leading to impairment of opsonizing antibodies and thus enhance bacterial survival in human...
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| Principais autores: | , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
BMC
2008-01-01
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| Serier: | BMC Microbiology |
| Online adgang: | http://www.biomedcentral.com/1471-2180/8/3 |
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