Neutrophil-derived reactive agents induce a transient SpeB negative phenotype in Streptococcus pyogenes

Abstract Background Streptococcus pyogenes (group A streptococci; GAS) is the main causative pathogen of monomicrobial necrotizing soft tissue infections (NSTIs). To resist immuno-clearance, GAS adapt their genetic information and/or phenotype to the surrounding environment. Hyper-virulent streptoco...

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Detalhes bibliográficos

Principais autores:	Patience Shumba, Thomas Sura, Kirsten Moll, Bhavya Chakrakodi, Lea A. Tölken, Jörn Hoßmann, Katharina J. Hoff, Ole Hyldegaard, Michael Nekludov, Mattias Svensson, Per Arnell, Steinar Skrede, INFECT Study Group, Anna Norrby-Teglund, Nikolai Siemens
Formato:	Artigo
Idioma:	Inglês
Publicado em:	BMC 2023-07-01
coleção:	Journal of Biomedical Science
Assuntos:	Streptococcus pyogenes Necrotizing soft tissue infections SpeB Neutrophils
Acesso em linha:	https://doi.org/10.1186/s12929-023-00947-x
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