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Repression of Rgg but not upregulation of LacD.1 in emm1-type covS mutant mediates the SpeB repression in group A Streptococcus

CovR/CovS is an important two-component regulatory system in human pathogen group A Streptococcus (GAS). Epidemiological studies have shown that inactivation of the sensor kinase CovS is correlated with invasive clinical manifestations. The phosphorylation level of response regulator CovR decreases...

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Principais autores: Chuan Chiang-Ni, Teng-Ping Chu, Jiunn-Jong Wu, Cheng-Hsun Chiu
Formato: Artigo
Idioma:Inglês
Publicado: Frontiers Media S.A. 2016-11-01
Series:Frontiers in Microbiology
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Acceso en liña:http://journal.frontiersin.org/Journal/10.3389/fmicb.2016.01935/full
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