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Effect of SpeB and EndoS from Streptococcus pyogenes on Human Immunoglobulins

Streptococcus pyogenes secretes a specific immunoglobulin G (IgG)-protease, SpeB, as well as the IgG glycan-hydrolyzing enzyme EndoS. Here we show that SpeB also degrades IgA, IgM, IgD, and IgE. We also show that EndoS only hydrolyzes the glycan moiety on native but not denatured IgG. Thus, SpeB has...

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Bibliografiset tiedot
Julkaisussa:Infect Immun
Päätekijät: Collin, Mattias, Olsén, Arne
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: American Society for Microbiology (ASM) 2001
Aiheet:
Linkit:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC100124/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11598100/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/IAI.69.11.7187-7189.2001
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