SpeB of Streptococcus pyogenes Differentially Modulates Antibacterial and Receptor Activating Properties of Human Chemokines

BACKGROUND: CXC chemokines are induced by inflammatory stimuli in epithelial cells and some, like MIG/CXCL9, IP–10/CXCL10 and I–TAC/CXCL11, are antibacterial for Streptococcus pyogenes. METHODOLOGY/PRINCIPAL FINDINGS: SpeB from S. pyogenes degrades a wide range of chemokines (i.e. IP10/CXCL10, I-TAC...

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Main Authors: Egesten, Arne, Olin, Anders I., Linge, Helena M., Yadav, Manisha, Mörgelin, Matthias, Karlsson, Anna, Collin, Mattias
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2009
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2652026/
https://ncbi.nlm.nih.gov/pubmed/19274094
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0004769
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