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The Human CXC Chemokine Granulocyte Chemotactic Protein 2 (GCP-2)/CXCL6 Possesses Membrane-Disrupting Properties and Is Antibacterial

Granulocyte chemotactic protein 2 (GCP-2)/CXCL6 is a CXC chemokine expressed by macrophages and epithelial and mesenchymal cells during inflammation. Through binding and activation of its receptors (CXCR1 and CXCR2), it exerts neutrophil-activating and angiogenic activities. Here we show that GCP-2/...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Linge, Helena M., Collin, Mattias, Nordenfelt, Pontus, Mörgelin, Matthias, Malmsten, Martin, Egesten, Arne
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology (ASM) 2008
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2443903/
https://ncbi.nlm.nih.gov/pubmed/18443119
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00028-08
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