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Bidirectional Crosstalk between C5a Receptors and the NLRP3 Inflammasome in Macrophages and Monocytes
C5a is an inflammatory mediator generated by complement activation that positively regulates various arms of immune defense, including Toll-like receptor 4 (TLR4) signaling. The NOD-like receptor pyrin domain-containing protein 3 (NLRP3) inflammasome is activated by pathogen products and cellular/ti...
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主要な著者: | , , , , |
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フォーマット: | Artigo |
言語: | Inglês |
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Hindawi Limited
2016-01-01
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シリーズ: | Mediators of Inflammation |
オンライン・アクセス: | http://dx.doi.org/10.1155/2016/1340156 |
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