Critical role for the NLRP3 inflammasome during acute lung injury()

The inflammasome is a key factor in innate immunity and senses soluble pathogen and danger associated molecular patterns as well as biological crystals (urate, cholesterol, etc.), resulting in expression of IL-1β and IL-18. Using a standard model of acute lung injury (ALI) in mice featuring airway i...

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Main Authors: Grailer, Jamison J., Canning, Bethany A., Kalbitz, Miriam, Haggadone, Mikel D., Dhond, Rasika M., Andjelkovic, Anuska V., Zetoune, Firas S., Ward, Peter A.
Formato: Artigo
Idioma:Inglês
Publicado: 2014
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4061751/
https://ncbi.nlm.nih.gov/pubmed/24795455
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1400368
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