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Critical role for the NLRP3 inflammasome during acute lung injury()
The inflammasome is a key factor in innate immunity and senses soluble pathogen and danger associated molecular patterns as well as biological crystals (urate, cholesterol, etc.), resulting in expression of IL-1β and IL-18. Using a standard model of acute lung injury (ALI) in mice featuring airway i...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4061751/ https://ncbi.nlm.nih.gov/pubmed/24795455 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1400368 |
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