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Critical role for C5aRs in the development of septic lymphopenia in mice()
In the early stages of sepsis, lymphocytes undergo apoptosis, resulting in lymphopenia and immunosuppression. The trigger for septic lymphopenia is unknown. Using the polymicrobial model of murine sepsis, we investigated the role of C5a receptors in septic lymphopenia. In wild type mice, CLP resulte...
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| Publicado no: | J Immunol |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4297720/ https://ncbi.nlm.nih.gov/pubmed/25539817 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1401193 |
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