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Selective Biological Responses of Phagocytes and Lungs to Purified Histones

Histones invoke strong proinflammatory responses in many different organs and cells. We assessed biological responses to purified or recombinant histones, using human and murine phagocytes and mouse lungs. H1 had the strongest ability in vitro to induce cell swelling independent of requirements for...

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Detalhes bibliográficos
Publicado no:J Innate Immun
Main Authors: Fattahi, Fatemeh, Grailer, Jamison J., Lu, Hope, Dick, Rachel S., Parlett, Michella, Zetoune, Firas S., Nuñez, Gabriel, Ward, Peter A.
Formato: Artigo
Idioma:Inglês
Publicado em: S. Karger AG 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5413366/
https://ncbi.nlm.nih.gov/pubmed/28171866
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1159/000452951
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