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A single-nuclei RNA sequencing study of Mendelian and sporadic AD in the human brain
Abstract Background Alzheimer’s disease (AD) is the most common form of dementia. This neurodegenerative disorder is associated with neuronal death and gliosis heavily impacting the cerebral cortex. AD has a substantial but heterogeneous genetic component, presenting both Mendelian and complex genet...
Αποθηκεύτηκε σε:
Κύριοι συγγραφείς: | , , , , , , , , , , , , , , , , , |
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Μορφή: | Artigo |
Γλώσσα: | Inglês |
Έκδοση: |
BMC
2019-08-01
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Σειρά: | Alzheimer’s Research & Therapy |
Θέματα: | |
Διαθέσιμο Online: | http://link.springer.com/article/10.1186/s13195-019-0524-x |
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