The TMEM106B FTLD-protective variant, rs1990621, is also associated with increased neuronal proportion

Apart from amyloid β deposition and tau neurofibrillary tangles, Alzheimer disease (AD) is a neurodegenerative disorder characterized by neuronal loss and astrocytosis in the cerebral cortex. The goal of this study is to investigate genetic factors associated with the neuronal proportion in health a...

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Vydáno v:Acta Neuropathol
Hlavní autoři: Li, Zeran, Farias, Fabiana G., Dube, Umber, Del-Aguila, Jorge L., Mihindukulasuriya, Kathie A., Fernandez, Maria Victoria, Ibanez, Laura, Budde, John P., Wang, Fengxian, Lake, Allison M., Deming, Yuetiva, Perez, James, Yang, Chengran, Bahena, Jorge A., Qin, Wei, Bradley, Joseph L., Davenport, Richard, Bergmann, Kristy, Morris, John C., Perrin, Richard J., Benitez, Bruno A., Dougherty, Joseph D., Harari, Oscar, Cruchaga, Carlos
Médium: Artigo
Jazyk:Inglês
Vydáno: 2019
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6942643/
https://ncbi.nlm.nih.gov/pubmed/31456032
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00401-019-02066-0
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