TREM2 brain transcript-specific studies in AD and TREM2 mutation carriers

BACKGROUND: Low frequency coding variants in TREM2 are associated with Alzheimer disease (AD) risk and cerebrospinal fluid (CSF) TREM2 protein levels are different between AD cases and controls. Similarly, TREM2 risk variant carriers also exhibit differential CSF TREM2 levels. TREM2 has three differ...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Mol Neurodegener
Main Authors: Del-Aguila, Jorge L., Benitez, Bruno A., Li, Zeran, Dube, Umber, Mihindukulasuriya, Kathie A., Budde, John P., Farias, Fabiana H. G., Fernández, Maria Victoria, Ibanez, Laura, Jiang, Shan, Perrin, Richard J., Cairns, Nigel J., Morris, John C., Harari, Oscar, Cruchaga, Carlos
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2019
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6505298/
https://ncbi.nlm.nih.gov/pubmed/31068200
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13024-019-0319-3
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