A single-nuclei RNA sequencing study of Mendelian and sporadic AD in the human brain

BACKGROUND: Alzheimer’s disease (AD) is the most common form of dementia. This neurodegenerative disorder is associated with neuronal death and gliosis heavily impacting the cerebral cortex. AD has a substantial but heterogeneous genetic component, presenting both Mendelian and complex genetic archi...

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Detalhes bibliográficos
Publicado no:Alzheimers Res Ther
Main Authors: Del-Aguila, Jorge L., Li, Zeran, Dube, Umber, Mihindukulasuriya, Kathie A., Budde, John P., Fernandez, Maria Victoria, Ibanez, Laura, Bradley, Joseph, Wang, Fengxian, Bergmann, Kristy, Davenport, Richard, Morris, John C., Holtzman, David M., Perrin, Richard J., Benitez, Bruno A., Dougherty, Joseph, Cruchaga, Carlos, Harari, Oscar
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2019
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6689177/
https://ncbi.nlm.nih.gov/pubmed/31399126
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13195-019-0524-x
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