A single-nuclei RNA sequencing study of Mendelian and sporadic AD in the human brain

BACKGROUND: Alzheimer’s disease (AD) is the most common form of dementia. This neurodegenerative disorder is associated with neuronal death and gliosis heavily impacting the cerebral cortex. AD has a substantial but heterogeneous genetic component, presenting both Mendelian and complex genetic archi...

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Bibliografiske detaljer
Udgivet i:Alzheimers Res Ther
Main Authors: Del-Aguila, Jorge L., Li, Zeran, Dube, Umber, Mihindukulasuriya, Kathie A., Budde, John P., Fernandez, Maria Victoria, Ibanez, Laura, Bradley, Joseph, Wang, Fengxian, Bergmann, Kristy, Davenport, Richard, Morris, John C., Holtzman, David M., Perrin, Richard J., Benitez, Bruno A., Dougherty, Joseph, Cruchaga, Carlos, Harari, Oscar
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2019
Fag:
Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6689177/
https://ncbi.nlm.nih.gov/pubmed/31399126
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13195-019-0524-x
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