A single-nuclei RNA sequencing study of Mendelian and sporadic AD in the human brain

BACKGROUND: Alzheimer’s disease (AD) is the most common form of dementia. This neurodegenerative disorder is associated with neuronal death and gliosis heavily impacting the cerebral cortex. AD has a substantial but heterogeneous genetic component, presenting both Mendelian and complex genetic archi...

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Dettagli Bibliografici
Pubblicato in:Alzheimers Res Ther
Autori principali: Del-Aguila, Jorge L., Li, Zeran, Dube, Umber, Mihindukulasuriya, Kathie A., Budde, John P., Fernandez, Maria Victoria, Ibanez, Laura, Bradley, Joseph, Wang, Fengxian, Bergmann, Kristy, Davenport, Richard, Morris, John C., Holtzman, David M., Perrin, Richard J., Benitez, Bruno A., Dougherty, Joseph, Cruchaga, Carlos, Harari, Oscar
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2019
Soggetti:
Research
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6689177/
https://ncbi.nlm.nih.gov/pubmed/31399126
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13195-019-0524-x
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