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Inhibition of O-acetylserine sulfhydrylase by fluoroalanine derivatives
O-acetylserine sulfhydrylase (OASS) is the pyridoxal 5′-phosphate dependent enzyme that catalyses the formation of L-cysteine in bacteria and plants. Its inactivation is pursued as a strategy for the identification of novel antibiotics that, targeting dispensable proteins, holds a great promise for...
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| Main Authors: | , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Taylor & Francis Group
2018-01-01
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| Serier: | Journal of Enzyme Inhibition and Medicinal Chemistry |
| Fag: | |
| Online adgang: | http://dx.doi.org/10.1080/14756366.2018.1504040 |
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