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IL-21 limits peripheral lymphocyte numbers through T cell homeostatic mechanisms.

IL-21, a member of the common gamma-chain utilizing family of cytokines, participates in immune and inflammatory processes. In addition, the cytokine has been linked to autoimmunity in humans and rodents.To investigate the mechanism whereby IL-21 affects the immune system, we investigated its role i...

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Detalhes bibliográficos
Main Authors: Shrimati Datta, Nora E Sarvetnick
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science (PLoS) 2008-09-01
Colecção:PLoS ONE
Acesso em linha:http://europepmc.org/articles/PMC2527999?pdf=render
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