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IL-21 Limits Peripheral Lymphocyte Numbers through T Cell Homeostatic Mechanisms

BACKGROUND: IL-21, a member of the common γ-chain utilizing family of cytokines, participates in immune and inflammatory processes. In addition, the cytokine has been linked to autoimmunity in humans and rodents. METHODOLOGY/PRINCIPAL FINDINGS: To investigate the mechanism whereby IL-21 affects the...

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Detalhes bibliográficos
Main Authors: Datta, Shrimati, Sarvetnick, Nora E.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2527999/
https://ncbi.nlm.nih.gov/pubmed/18773086
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0003118
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