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Disruption of SUMO-specific protease 2 induces mitochondria mediated neurodegeneration.
Post-translational modification of proteins by small ubiquitin-related modifier (SUMO) is reversible and highly evolutionarily conserved from yeasts to humans. Unlike ubiquitination with a well-established role in protein degradation, sumoylation may alter protein function, activity, stability and s...
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| Hlavní autoři: | , , , , , , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
Public Library of Science (PLoS)
2014-10-01
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| Edice: | PLoS Genetics |
| On-line přístup: | http://europepmc.org/articles/PMC4191884?pdf=render |
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