Disruption of SUMO-Specific Protease 2 Induces Mitochondria Mediated Neurodegeneration

Post-translational modification of proteins by small ubiquitin-related modifier (SUMO) is reversible and highly evolutionarily conserved from yeasts to humans. Unlike ubiquitination with a well-established role in protein degradation, sumoylation may alter protein function, activity, stability and s...

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Bibliografiske detaljer
Main Authors: Fu, Jiang, Yu, H.-M. Ivy, Chiu, Shang-Yi, Mirando, Anthony J., Maruyama, Eri O., Cheng, Jr-Gang, Hsu, Wei
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2014
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4191884/
https://ncbi.nlm.nih.gov/pubmed/25299344
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1004579
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