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Disruption of SUMO-specific protease 2 induces mitochondria mediated neurodegeneration.

Post-translational modification of proteins by small ubiquitin-related modifier (SUMO) is reversible and highly evolutionarily conserved from yeasts to humans. Unlike ubiquitination with a well-established role in protein degradation, sumoylation may alter protein function, activity, stability and s...

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Detalhes bibliográficos
Main Authors: Jiang Fu, H-M Ivy Yu, Shang-Yi Chiu, Anthony J Mirando, Eri O Maruyama, Jr-Gang Cheng, Wei Hsu
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science (PLoS) 2014-10-01
Colecção:PLoS Genetics
Acesso em linha:http://europepmc.org/articles/PMC4191884?pdf=render
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