SIRT7 Deacetylates STRAP to Regulate p53 Activity and Stability

Serine-threonine kinase receptor-associated protein (STRAP) functions as a regulator of both TGF-β and p53 signaling that participates in the regulation of cell proliferation and cell death in response to various stresses. Here, we demonstrate that STRAP acetylation plays an important role in p53-me...

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Detalhes bibliográficos
Main Authors: Miao Yu, Xiaoyan Shi, Mengmeng Ren, Lu Liu, Hao Qi, Chi Zhang, Junhua Zou, Xiaoyan Qiu, Wei-Guo Zhu, Ying E. Zhang, Wengong Wang, Jianyuan Luo
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI AG 2020-06-01
Colecção:International Journal of Molecular Sciences
Assuntos:
SIRT7
STRAP
p53
acetylation
5-FU treatment
Acesso em linha:https://www.mdpi.com/1422-0067/21/11/4122
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